She did leave the house with the expectation of going on a shopping date. It isn't surprising it took her a bit to decide to actually take this seriously.
Spoiler spoiler: She gets better. Well, depending on your definition of better, since we did actually experience a stable time loop where Himeko died and Trailblazer looped their journey to the point to be able to prevent the death.
If those are metastatized lung cancer, sure. (breasts has been one of the earliest metastatizing site for lung cancer due to the lymph nodes connecting them)
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