No, I think she's just one of those people who you absolutely, positively cannot leave anywhere near the shiny red buttons.
Obviously, you should handle Mao using the Overlord's Checklist mentality - the big shiny red button that says "Self Destruct" will instead cause a jet of water to spray whoever pushes the button. If it is somehow necessary to have a self destruct button, it will instead be a plain button labeled "sewage ventilation".
It was nothing, really.What have you done!?
You utter buffoon!We're here!That's the Mountain Witch's house over there.Thank you, Oniguma-san!Even guiding us around!Mao-chan...MAO-CHAAAN!Feels like this is no laughing matter, doesn't it...Rampaging Bear PoseOkay, Mao-chan, let's... go...?