At least to my knowledge, most eldritch abominations are likely to pass each other by as what they want or how they interact with the world is so different as to eliminate the need of conflict. Not that they don't have issues to deal with but an eldritch abomination in this context isn't going to bring about fields of flowers and cute puppy dogs.
i don't see any problems fro QB if Saya turn her program on for this world. After all it doesn't matter how "girls" would look like as long as they have souls.