Even though the Yuri tag is used on Pixiv, I'm lost with this one. Can anyone help?

Apparently, the coughing up flowers comes from a manga named "Hanahaki Otome", where it's a disease caused by unrequited love.

Tapper said:

Apparently, the coughing up flowers comes from a manga named "Hanahaki Otome", where it's a disease caused by unrequited love.

I vaguely remember something like this, rather depressing now that I've thought about it