Is there anything making this Fate/Grand Order in particular rather than just Medjed in general? I don't know enough about FGO to know if this is referencing something specific.

Possible since fgo made it a thing again. but in my heart there will always be an RJ under that blanket

It's not fate related. The commentary is talking about how ancient Egypt knew of the existence of shoebills, hence the Medjed in the picture.