Unlikely Fusion? Touhou is popular, Jojo is popular, and the former has a ton of shout-outs to the latter.
If its specifically about the characters, then more so: Rinnosuke is a kind of Yare, Yare Daze kind of guy already in c/fanon, and Yukari is as obnoxious as Dio and constantly bugs Rinnosuke.
Yukari: Kissing me Yukari is very good! Rinnosuke: Who in FACE are you!? Yukari: you have offended the great and cool yukari please say sorry Rinnosuke: ABAJABAJABAJABAJABAJABAJABAJ
