It's pretty obvious from this picture that someone has royally pissed Miko off. So much so that she's finally dropped that false persona of a wise and virtuous leader and revealed her true self - a greedy and wicked beast ready to strike, ready to kill for her own selfish desires.
This is the Miko that started a war just to subjugate her own people, the Miko that unintentionally destroyed her own body in pursuit of her goals.
The Miko that recognizes neither the rights or worth of others beyond their immediate use to her nor the value of discretion when dealing with dangerous people (*cough*Seiga*cough*) and their snake oil, but only the object of her unquellable avarice.
Whoever it is that has her immediate attention has foolishly (righteously?) placed his or herself between Miko and whatever it is that she covets.