Oripathy lesions are black crystals. Characters have had secondary mutations from getting oripathy, like Estelle growing massive horns, before.
But Toddifons has red crystals. From her in-game info:
Generally speaking, crystal deposits on Infected settle into a black hue, this being Originium's original color. But under special circumstances, crystal coloration and even manner of formation can exhibit change. We still aren't clear as to what brings about these sudden changes. Further and deeper research is required.
But Toddifons has red crystals. From her in-game info:
Maybe originium in Endfield works differently?
No, it still works the same. Originium will only work differently if the patient has different vital functions, just like Doctor which is probably immune to them (being a 'human' in truest sense) or beings like Conviction/Nian and her extended families/'gods' like Kjera.