It took me only two long weeks, but finally I managed to kill her...
After dozens and dozens of failed attempts using the north route (didn't felt like using the southern route while using both support expeditions) on E-2, I've pretty much said "fuck it" and replaced CVLs (Hiyou and Jun'you) with CV and sacrificed a bit of LOS and Air Superiority for some dive bombers and things became suprisingly smooth for me (admittedly I used support expedition so my kanmusu could focus on the troll Flagships Wo and Ru).
Finished with: Ooi Kai Ni (Type 32 and Type 33 radars plus midget sub), Haruna Kai Ni and Kirishima Kai Ni (both used 46cm gun, 41cm gun, Type 0 seaplane and Type 3 shell), Haguro Kai Ni (2x 20.3cm(no.2) gun, Type 0 seaplane and Type 3 shell), Taihou Kai (Reppu x2, Type 99 Egusa bomber and Saiun) and Hiryuu Kai Ni (Saiun, Reppu Kai, Type 99 skilled bomber and another Saiun).
Unfortunately since I used way too many of my high-level kanmusu just to clear E-1 and E-2, I'm pretty much incapable of doing MI now (and even if I had enough veteran kanmusus at hand, I would probably be too much sick and tired to do it anyway)... Damn you, developers.